Cytokeratin 1 anticorps

N° du produit ABIN6297655

Cet anticorps Souris Monoclonal détecte spécifiquement Cytokeratin 1 dans IHC. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Cytokeratin 1 anticorps (ABIN6297655)

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Cytokeratin 1 anticorps

Fonction: Mouse anti-Human/Mouse/Rat HMW Cytokeratin Antibody [IHC only]

Specificité: Cytoplasmic

Purification: Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.

Immunogène: Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Cytokeratin 1

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Autre désignation: Keratin, type II cytoskeletal 1

Sujet:

Target Description: This antibody recognizes HMW Keratin 1, 5, 10 and 14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. The HMW Cytokeratin antibody shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this mAb. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. It has also been useful in separating benign from malignant intraductal breast proliferations.

Gene Symbol: KRT1///KRTA

ID gène: 3848

UniProt: P04264